Castanospermine a Possible AIDS Treatment

Isoniazid Prevention Treatment in People With AIDS

این مقاله قصد دارد به ارائه دهندگان مراقبت بهداشتی در مورد استفاده از درمان پیشگیری کننده ایزونیازید در افراد مبتلا به عفونت ویروسی نقص ایمنی انسانی (HIV) کمک نماید. در حال حاضر اطلاعات کافی جهت توصیه اجرای درمان پیشگیری کننده سل، برای افراد مبتلا به هر دو عفونت در سری برنامه های جهانی وجود ندارد و باید منتظر اطلاعات دقیق تری بر تاثیر درمان پیشگیری کننده و بخصوص صرفه اقتصادی و راحتی مصرف آن بود...

Asymmetric syntheses of 1-deoxy-6,8a-di-epi-castanospermine and 1-deoxy-6-epi-castanospermine.

Asymmetric syntheses of both 1-deoxy-6,8a-di-epi-castanospermine and 1-deoxy-6-epi-castanospermine, polyhydroxylated indolizidine alkaloids that act as selective glycosidase inhibitors, have been accomplished in seven steps. The key feature of our unique syntheses includes the stereoselective introduction of the C-3 and C-4 hydroxyl groups utilizing the aza-Claisen rearrangement-induced ring ex...

Fighting HIV/AIDS: is success possible?

The fight against HIV/AIDS poses enormous challenges worldwide, generating fears that success may be too difficult or even impossible to attain. Uganda has demonstrated that an early, consistent and multisectoral control strategy can reduce both the prevalence and the incidence of HIV infection. From only two AIDS cases in 1982, the epidemic in Uganda grew to a cumulative 2 million HIV infectio...

An HIV/AIDS Prophylactic vaccine is possible

One needs to think outside of the box, as one of us (Ronald B Luftig) learned from many years as a mathematician, and a biophysicist.In this short Review, the need to focus on producing high levels of neutralizing antibodies (NAbs) to incoming and conformationally altered virus after it has bound to CD4+ cells is essential.Increasing the number of gp120 molecules on the surface of L-2 particles...

1 AIDS TREATMENT national aids manual